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Анотація
Анотація. Розсіяний склероз (РС) — це хронічне автоімунне захворювання, яке характеризується деградацією мієліну — критично важливого компонента аксонів у центральній нервовій системі (ЦНС). Демієлінізація порушує передачу нервових імпульсів, що призводить до серйозних неврологічних порушень. Незважаючи на досягнення в галузі імуномодулюючої терапії, на сьогодні не існує методів лікування, які б безпосередньо відновлювали передачу сигналів через демієлінізовані аксони. Цей комплексний огляд присвячений дослідженню новітніх технологій, спрямованих на подолання цієї незадоволеної медичної потреби. Розглядаються інноваційні підходи, такі як біоінженерні замінники мієліну, нанотехнологічні втручання та методи електричної стимуляції, що мають на меті сприяння функціональному відновленню. Окрім того, аналізуються досягнення у галузі терапії стовбуровими клітинами та використання фармакологічних засобів, спрямованих на ремієлінізацію, в контексті доклінічних та клінічних досліджень. На основі синтезу сучасних наукових результатів, у цьому огляді висвітлюються ключові виклики, зокрема біосумісність, цільова доставка та довготривала ефективність, а також визначаються перспективні напрямки подальших інновацій. Отримані висновки підкреслюють важливість міждисциплінарної співпраці для розробки проривних методів лікування, здатних відновити неврологічні функції та покращити якість життя людей, які страждають на РС.
Ключові слова:
Демієлінізація, Передача сигналу, Розсіяний склероз, Ремієлінізація, Нейровідновлення
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Як цитувати
AGJ, C., B, H., & FMMT, M. (2025). INVESTIGATING A TECHNOLOGY TO RESTORE SIGNAL TRANSMISSION ACROSS DEMYELINATED AXONS IN MULTIPLE SCLEROSIS: A COMPREHENSIVE REVIEW. Automation of Technological and Business Processes, 17(1), 88-97. https://doi.org/10.15673/atbp.v17i1.3092
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МЕТОДИ ТА АЛГОРИТМИ ЕФЕКТИВНОГО УПРАВЛІННЯ ОБ‘ЭКТАМИ
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